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    《2010GMCN英國(guó)骨髓增生異常綜合征診療指南》內(nèi)容簡(jiǎn)介：

    Patients should normally be ***rmed of the diagnosis by a consultant haematologist according to theindividual Trust's Breaking Bad News guidelines. Written ***rmation should be given to thepatient/relative as appropriate. Patients should be offered additional counselling/support from trainednurse counsellors and clinical psychologists. In elderly patients specific support services for this agegroup should also be offered.

    《2010GMCN英國(guó)骨髓增生異常綜合征診療指南》內(nèi)容預(yù)覽：

    MANAGEMENT OF THROMBOCYTOPAENIA

    Administration of platelet concentrates is indicated for active bleeding and for support during acuteepisodes of infection or during chemotherapy. Platelet transfusion is not routinely recommended forchronically depressed platelet counts per se. Antifibrinolytic agents may be useful in selected cases.Patients with severe thrombocytopenia may be eligible for clinical trials of newer agents or respond todemethylating agents and other therapeutic interventions.

    MANAGEMENT OF INFECTION

    Individual patients may require antibacterial or antifungal prophylaxis if severely neutropenic but thereare no published data to support the routine use of these drugs in this situation. Consideration shouldbe given to the use of prophylactic low dose GCSF therapies in severely neutropenic patients whereappropriate. Neutropenic sepsis in MDS patients should be treated vigorously with intravenousantibiotics and growth factors according to local protocols as appropriate and BCSH guidelines.

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